In her research Tsang has investigated the equation of state and liquid gas phase transition of nuclear matter, the production of rare isotopes, and single particle structure of the nucleus via transfer reactions. Since 1980, she has published nearly 200 articles in refereed journals and has given numerous talks at international conferences. Her work has involved collaborations of scientists from China, Brazil, Canada, France, Germany, Italy, Japan, Russia, and Vietnam. She has organized numerous conferences with international participants.
Before the use of the internet became wide spread, she coordinated the publication and distribution of the “Nuclear Physics Preprints” whose target readership included many scientists in the third world. She has served as the chair of the Committee on the International Freedom of Scientists (1995) and on Division of Nuclear Physics Program Committee (1996-1997). In 2000, she received the Heinz Pagels award from the New York Academy of Sciences for her work on behalf of Chinese dissidents.