Micro-colony of Bacteria

;9 Lev Tsimring 2014
Arthur Prindle (UCSD), Jeff Hasty (UCSD), Lev Tsimring (UCSD)

A periodic sequence of fluorescent flashes in a microfluidic device contains hundreds of micro-colonies of bacteria E.coli with synthetic gene circuits that generate periodic oscillations of gene expression. The colonies communicate and synchronize by producing and responding to bursts of hydrogen peroxide.

Paragraph of explanation: UCSD researchers use biological "parts" to engineer small gene circuits within living cells that demonstrate complex dynamical behavior. This image shows one of a periodic sequence of fluorescent flashes in a microfluidic device containing hundreds of microcolonies of bacteria E.coli with synthetic gene circuits that generate periodic oscillations of gene expression. The colonies communicate and synchronize by producing and responding to bursts of hydrogen peroxide.

Related Abstract

Gray arrow  http://meetings.aps.org/Meeting/MAR14/Event/218104